Updated: 2024-12-31 11:24:14
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 31st , 2024 A CpG Oligodeoxynucleotide Promotes Bone Formation Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Bone is constantly remodeled by the activities of osteoclasts and osteoblasts Osteoclasts break down the extracellular matrix of bone ,
Updated: 2024-12-31 11:05:54
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 31st , 2024 Lithocholic Acid in Calorie Restriction Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Researchers here argue for lithocholic acid a bile acid produced when the gut microbiome processes bile , to be a player in the ability of calorie
Updated: 2024-12-30 11:15:05
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 30th , 2024 Urolithin A Derivatives Targeting Mitophagy in Clinical Trials Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment While there seems to be no firmly established mechanism by which urolithin A acts to modestly improve mitochondrial function ,
Updated: 2024-12-30 11:11:40
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 30th , 2024 Developing a Cell Model of Aging-Like Mitochondrial Mutational Damage Permalink With Comments Permalink No Comments Posted by Reason Read 1 Comment Add a Comment Mitochondria are the power plants of the cell , the distant descendants of symbiotic bacteria that carry their own small
Updated: 2024-12-29 11:47:01
, Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 29th , 2024 Fight Aging Newsletter , December 30th 2024 Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Fight Aging publishes news and commentary relevant to the goal of ending all age-related disease , to be achieved by bringing the mechanisms of
Updated: 2024-12-27 19:50:05
, Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 27th , 2024 MileAge , a Metabolomic Aging Clock Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Any sufficiently large database of biological data obtained from individuals of different ages can be used to build an aging clock Machine learning
Updated: 2024-12-27 11:22:37
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 27th , 2024 Approaches to Targeting Phosphorylated Tau Protein in the Aging Brain Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Tau protein in the brain can become overly phosphorylated and the resulting clumped proteins form solid aggregates that
Updated: 2024-12-27 11:11:46
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help December 27th , 2024 Worse Vascular Health Accelerates a Measure of Brain Aging Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Worse cardiovascular function is known to correlate with risk of neurodegenerative conditions Evidence points to a range of
Updated: 2024-12-23 18:50:51
Researchers have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD). The study highlights microglia, the brain's primary immune cells, as central players in both the protective and harmful responses associated with the disease.
Updated: 2024-12-20 18:29:00
Using an AI tool, researchers have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.
Updated: 2024-12-19 20:24:57
A new study reveals significant improvements in the health of older adults when compared to previous generations.
Updated: 2024-12-19 20:19:02
Phase I clinical trial of a drug was successfully completed, with promise to treat Alzheimer's and other neurodegenerative diseases. The compound, named VU319, is the first end-to-end drug discovery effort related to memory loss, starting from the earliest basic science research through human clinical trials.
Updated: 2024-12-18 22:48:45
Researchers have conducted a comprehensive study to evaluate artificial intelligence based aging clocks, which predict health and lifespan using data from blood.
Updated: 2024-12-11 19:39:02
People around the globe are living longer -- but not necessarily healthier -- lives, according to new research. A study of 183 World Health Organization (WHO) member countries found those additional years of life are increasingly fraught with disease.
Updated: 2024-12-06 21:19:51
Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases with real-world patient data to identify FDA-approved drugs that may be repurposed to target disease-associated microglia in Alzheimer's disease without affecting the healthy type.
Updated: 2024-12-06 16:19:46
A groundbreaking study has created the world's largest and most geographically comprehensive international norms for handgrip strength, enabling global peer-comparison, health screening and surveillance across the adult lifespan.
Updated: 2024-12-05 19:30:02
New research has found that women who have had both ovaries surgically removed before the age of 50 and carry a variant of the apolipoprotein gene, the APOE4 allele, are at high risk of late-life Alzheimer disease (AD). Use of hormone therapy mitigates this risk.
Updated: 2024-12-04 19:54:05
A laboratory study provides evidence about how advanced age can be protective against cancer -- with implications for treating patients in different age groups.
Updated: 2024-12-04 16:36:37
Researchers have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD). This innovative tool analyzes biomarkers that can induce 3D structural changes in proteins, providing critical insights into disease mechanisms and highlighting potential targets for therapeutic intervention. The findings could lead to advancements in early detection and treatment strategies for Alzheimer's disease, which has long eluded effective therapies.
Updated: 2024-12-03 20:39:36
A research team has discovered that accumulated DNA damage in the retina is a key contributor to age-related macular degeneration and that targeting specific retinal cell types may lead to treatments that slow or stop progression.
