Updated: 2024-07-31 18:52:31
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help July 31st , 2024 Cellular Reprogramming via Gene Therapy Improves Memory Function in Old Rats Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment A number of groups have demonstrated that selectively exposing aged rodent tissues to expression of the Yamanaka
Updated: 2024-07-31 10:22:39
Rapamycin is arguably the best of the calorie restriction mimetic drugs so far tested in mice. It slows aging robustly in animal studies, and has been used in humans at much higher doses than the anti-aging dose (around 5mg once per week) for decades. Still, there is a lack of human trials conducted for the purposes of slowing aspects of aging. More trial data than the little that presently exists would increase the number of physicians willing to prescribe off-label for anti-aging purposes. The specific focus of the trial doesn't much matter so long as the researchers measure enough data to assemble biomarkers of aging and general health. So, for example, one might look at a recently launched study of gum disease in older patients, […]
Updated: 2024-07-31 10:11:51
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help July 31st , 2024 Towards a Genetically Engineered Gut Microbiome Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The gut microbiome influences long-term health . The balance of microbial populations shifts with age to become more harmful , certainly more
Updated: 2024-07-30 18:19:50
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help July 30th , 2024 Positive Functions of Possibly Senescent p16-Expressing Immune Cells in Disease Tolerance Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment It has been a question for some time as to whether immune cells expressing p16 and β-galactosidase
Updated: 2024-07-30 10:22:39
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help July 30th , 2024 Neural Epigenetic Aging as a Driver of Cognitive Decline Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Ever-shifting epigenetic marks on the genome determine its structure in the cell nucleus and thus which portions of the genome are
Updated: 2024-07-30 10:02:41
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help July 30th , 2024 Considering the Gut Microbiome's Influence on Astrocytes in the Aging Brain Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The influence of the gut microbiome on the long-term trajectory of health is a popular topic these days . Tools for
Updated: 2024-07-29 18:35:01
Polyadenylation occurs during the creation of messenger RNA (mRNA). It is one part of the complex processes of transcription of the DNA sequence for a gene and assembly of the resulting RNA molecule. In the polyadenylation process, a tail of repeated adenine bases - called the poly(A) tail - is appended to the mRNA molecule. This protects the mRNA from degradation once it has left the nucleus, and also helps in other ways with the process of translation, in which the mRNA molecule is used as a blueprint by a ribosome to assemble protein molecules from amino acids. Changes in the length of the mRNA tail will affect levels of protein production, and thus the behavior of cells. In today's open access paper, researchers report […]
Updated: 2024-07-29 15:02:41
Losing someone close, like a family member, can make you age faster. The study found that people who lost a parent, partner, sibling, or child, showed signs of older biological age compared to those who hadn't experienced such losses.
Updated: 2024-07-29 10:22:25
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help July 29th , 2024 Meta-Analysis Suggests a Declining Trend in Dementia Incidence Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Researchers here conduct a meta-analysis of systemic reviews of dementia incidence over time . The results indicate that the risk of
Updated: 2024-07-29 10:11:03
The characteristic loss of muscle mass and strength that occurs with age leads to sarcopenia and frailty. While a few companies are targeting this age-related muscle loss via development of small molecule drugs, the recent history of this part of the field is not encouraging. None of the attempted approaches have yet improved on exercise. That may well be due to a failure to specifically target underlying mechanisms that drive degenerative aging, projects instead relying on the sort of adjustments to metabolism that are discussed in the paper referenced here, but only time will tell. A healthy lifespan relies on independent living, in which active skeletal muscle is a critical element. The cost of not recognizing and acting earlier on unhealthy or aging muscle could […]
Updated: 2024-07-29 04:52:08
Researchers have found a link between following a diet that is rich in vitamins and minerals, especially one without much added sugar, and having a younger biological age at the cellular level.
Updated: 2024-07-28 11:32:08
, Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help July 28th , 2024 Fight Aging Newsletter , July 29th 2024 Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Fight Aging publishes news and commentary relevant to the goal of ending all age-related disease , to be achieved by bringing the mechanisms of aging
Updated: 2024-07-24 21:15:45
People with high levels of body fat stored in their belly or arms may be more likely to develop diseases like Alzheimer's and Parkinson's than people with low levels of fat in these areas, according to new research. The study also found that people with a high level of muscle strength were less likely to develop these diseases than people with low muscle strength.
Updated: 2024-07-18 04:46:34
A naturally occurring peptide called PEPITEM could potentially rejuvenate the immune response in older individuals and protect against 'inflammageing', which is widely believed to be the root cause of many age-related diseases. A study raises the exciting possibility of a protective agent that could dampen age-related inflammation and restore normal immune function in older adults.
Updated: 2024-07-17 04:10:28
Researchers have found that intense stress can be felt at the cellular level and is linked to negative physical and mental health effects.
Updated: 2024-07-17 04:10:07
Researchers have established new criteria for a memory-loss syndrome in older adults that specifically impacts the brain's limbic system. It can often be mistaken for Alzheimer's disease.
Updated: 2024-07-17 04:09:07
Scientists have discovered that 'switching off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25 percent.
Updated: 2024-07-16 19:11:53
In a new analysis of data, researchers have found that taking a daily supplement containing antioxidant vitamins and minerals slows progression of late-stage dry age-related macular degeneration (AMD), potentially helping people with late-stage disease preserve their central vision.
Updated: 2024-07-16 04:27:09
Hormone modulating therapy (HMT) used for the treatment of breast cancer was associated with a 7% lower risk of developing Alzheimer's disease and related dementias later in life, according to a new study.
Updated: 2024-07-10 23:53:30
A new study looks at predicting how quickly people with early Alzheimer's disease will experience cognitive decline. The study also looked at how the new drugs recently approved for the disease may reduce decline.
Updated: 2024-07-10 04:20:13
A longitudinal study has found that high-intensity interval exercise improves brain function in older adults for up to 5 years.
