Updated: 2024-04-25 10:22:49
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 25th , 2024 Extracellular Vesicles from Young Plasma Produce Benefits in Old Mice Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The evidence for transfusion of young plasma to produce benefits in old animals and human patients is mixed Despite
Updated: 2024-04-25 10:11:33
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 25th , 2024 The Rodent Aging Interventions Database Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment You might compare the LEV Foundation's Rodent Aging Interventions Database with the DrugAge database , both emerging from the efforts of researchers who
Updated: 2024-04-24 19:11:27
A variety of approaches show some promise in improving the function of stem cells in aged tissues. Stem cell populations support their tissue by providing a supply of daughter somatic cells to replace losses. This supply diminishes over time as stem cells reduce their activity for reasons that descend from the known root causes of aging, but which are not fully understood in detail. To the degree that reduced stem cell function is a response to the aged environment rather than a consequence of damage inherent to these cells, then it is useful to find ways to force stem cells to be more active. Whether this is the case may differ for different cell types, but there is ample evidence for interventions that can at […]
Updated: 2024-04-24 10:22:49
In recent years, researchers have been putting more effect into analyses of the CALERIE 2 study of human calorie restriction. The study took place some years ago, but new results continue to be published. Here, researchers show that effects on telomere length and a related aging clock are inconclusive. Telomere length measured in the white blood cells of a blood sample is not a great measure of aging. It is highly variable between individuals, is influenced day to day changes in immune status, and it takes a fairly large study group for age-related trends to show up. It has rightfully been eclipsed by the development of aging clocks derived from omics data. Caloric restriction (CR) modifies lifespan and aging biology in animal models. The Comprehensive […]
Updated: 2024-04-24 10:11:43
Researchers here report on the results of transfusion of young rat plasma into old rats, starting every other week in later life. The study is small, and is one more data point to add to a mixed set of results. Plasma transfusion from young individual to old individual doesn't look that impressive, all told, either in animals or in human patients. That doesn't appear to be discouraging the community of researchers and developers who continue to work on approaches to transfusion that they believe may move the needle. The example here is a straightforward approach to transfusion, the procedure conducted every other week, and is one of the studies in which the intervention appears to work well enough to be interesting. There is converging evidence […]
Updated: 2024-04-23 18:49:35
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 23rd , 2024 The Role of Immune Aging in Neurodegenerative Conditions Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The research community has come to see chronic inflammation and other age-related immune system dysfunctions as an important aspect of
Updated: 2024-04-23 10:22:19
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 23rd , 2024 Ambitious Goals at Mitrix Bio Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Mitrix Bio is one of the companies developing the means to produce large amounts of mitochondria for transplantation . Cells will take up new mitochondria from the
Updated: 2024-04-23 10:10:53
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 23rd , 2024 Investigating the Mechanisms of Very Early Alzheimer's Disease Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Researchers here look at cellular dysfunction that may form the earliest stages of Alzheimer's disease prior to the accumulation of
Updated: 2024-04-22 19:01:33
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 22nd , 2024 A Decline in Stemness in Many Human Stem Cell Populations with Aging Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Like the accumulation of senescent cells loss of stem cell function is a problematic feature of aging . Also like the
Updated: 2024-04-22 10:22:44
, , Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 22nd , 2024 Exercise , Stress , and Cardiovascular Risk Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Exercise is well known to correlate with reduced risk of cardiovascular disease in human epidemiological studies . In animal studies , it is
Updated: 2024-04-22 04:07:09
A specific protein, TP53INP2, might prevent muscle loss associated with aging. A new study indicates that high levels of this protein are linked to greater muscle strength and healthier aging. This discovery paves the way for new treatments that could enhance the quality of life for the elderly.
Updated: 2024-04-22 04:06:21
Middle-aged and older adults believe that old age begins later in life than their peers did decades ago, according to a new study.
Updated: 2024-04-17 22:28:16
The rate at which human cells age is influenced by multiple interconnected factors. New research examined how restricting calories influences telomere length and biological aging.
Updated: 2024-04-17 22:27:03
In a new study, researchers show that elevated levels of proteins related to cellular senescence, or aging, in the blood and the placenta are linked to this form of heart failure.
Updated: 2024-04-15 15:05:38
The first comprehensive cell atlas of aging human muscle reveals the intricate genetic and cellular processes behind muscle deterioration and mechanisms to counteract it.
Updated: 2024-04-10 15:27:17
Researchers have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for diseases that lead to accelerated aging as well as a means to counteract aging in healthy people by controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.
Updated: 2024-04-10 15:27:06
Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.
Updated: 2024-04-08 19:04:49
Pregnancy may carry a cost, reports a new study. The research shows that women who reported having been pregnant looked biologically older than women who had never been pregnant, and women who had been pregnant more often looked biologically older than those who reported fewer pregnancies.
Updated: 2024-04-05 17:04:46
Certain RNA molecules in the nerve cells in the brain last a life time without being renewed. Neuroscientists have now demonstrated that this. RNAs are generally short-lived molecules that are constantly reconstructed to adjust to environmental conditions. The research group hopes to decipher the complex aging process of the brain and gain a better understanding of related degenerative diseases.
Updated: 2024-04-02 18:03:21
Cell damage from oxidative stress is a major underlying cause of age-related cognitive and muscle strength decline. Antioxidants can reduce oxidative stress and prevent age-related health decline. A new study has found that mice administered with a blended antioxidant supplement show significant improvements in spatial cognition, short-term memory, and mitigated age-related muscle decline. The study suggests that blended antioxidant supplements hold promise as a dietary intervention for health issues associated with aging.
