Updated: 2025-01-22 11:22:53
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help January 22nd , 2025 Senolytic Treatment Reduces Periodontal Bone Loss in Aged Mice Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Senescent cells accumulate with age in tissues throughout the body , and their pro-inflammatory signaling becomes increasingly
Updated: 2025-01-22 11:03:54
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help January 22nd , 2025 Hearing Impairment Correlates with Risk of Parkinson's Disease Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Hearing loss has been correlated with the risk of numerous forms of neurodegenerative condition There are many studies similar to
Updated: 2025-01-21 18:11:32
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help January 21st , 2025 Cyclarity Therapeutics to Start a First Human Trial for Clearance of 7-ketocholesterol Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment A quarter of humanity dies from heart attack and stroke caused when an atherosclerotic plaque ruptures to
Updated: 2025-01-21 11:22:12
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help January 21st , 2025 An Assessment of Inflammatory Regulators in Monocytes Demonstrates the Complexity of Immune Aging Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment At the high level , we can say that the immune system becomes less capable and more
Updated: 2025-01-21 11:11:58
The ovaries exhibit significant age-related loss of function somewhat ahead of the rest of the body. Why is this the case? There is no good answer at present as to why the underlying mechanisms of aging produce a faster decline in the ovaries. The ability to compare the biochemistry of aging in the ovaries with the biochemistry of aging in the rest of the body may be an opportunity to learn something about aging more generally, however. So one sees papers such as this one, in which researchers review what is known of the mitochondrial dysfunction associated with aging specifically in the ovaries versus its role in aging elsewhere in the body. Ovarian aging is a major health concern for women. Ovarian aging is associated […]
Updated: 2025-01-21 05:58:01
Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million individuals.
Updated: 2025-01-21 05:57:54
Two major theories of aging both involve DNA, but in very different ways. Researchers have revealed that these theories may not be so different after all.
Updated: 2025-01-20 19:29:54
It is probably fair to say that the majority of work conducted to date on the treatment of aging as a medical condition has focused on mimicking and enhancing beneficial cellular responses to stresses such as lack of nutrients, heat, cold, toxins, and so forth. The bounds of the possible are illustrated by the results of regular exercise and the practice of calorie restriction. These interventions trigger all of the stress response mechanisms, so it seems unlikely that researchers will greatly improve on their performance with a therapy that targets only one of those mechanisms, or only one of the many regulators governing a given response mechanism. Both exercise and calorie restriction only slow the progression of aging, and are far removed from anything we […]
Updated: 2025-01-20 11:22:36
The assembly, processing, and activities of RNA molecules in the cell is a vast topic, even if narrowed to just one part of the body. A short paper can really only briefly summarize the primary areas of interest for researchers involved in the study of neurodegenerative conditions, as is the case here. Transcription of genes to produce RNA molecules is the first step in gene expression, and sweeping changes in gene expression take place with age. A cell is a state machine, its state largely determined by which RNAs and proteins are produced, and in what amount, at any given time. The state of cells determines the function of tissues. Even just the RNA portion of this picture is an enormously complex, incompletely understood soup […]
Updated: 2025-01-20 11:11:58
One of the benefits of physical fitness and the physical activity required to sustain that fitness is a slower aging of the brain. Human data provides only correlational data, but animal studies have demonstrated causation in the improved health and slowed aspects of aging resulting from exercise. Researchers here delve into the biochemistry of aging in brain and body cells, finding a great deal more downregulation of gene expression in the brain than elsewhere in the body with aging, and that physical exercise can reduce the extent of those changes. It is been noted that the expression levels of numerous genes undergo changes as individuals age, and aging stands as a primary factor contributing to age-related diseases. In this study, we screened for aging genes […]
Updated: 2025-01-19 11:11:02
, Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help January 19th , 2025 Fight Aging Newsletter , January 20th 2025 Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Fight Aging publishes news and commentary relevant to the goal of ending all age-related disease , to be achieved by bringing the mechanisms of
Updated: 2025-01-17 19:19:17
One of the many reasons to think that chronic inflammation is an important aspect of degenerative aging is that extremely old individuals, those who have outlived more than 99% of their birth cohort, tend to exhibit levels of inflammation that are similar to those of younger adults. A number of studies of centenarians (100 years and older), semi-supercentenarians (105 years and older) and supercentenarians (110 years and older) have noted unusually low levels of inflammatory markers, typically lower than the inflammation normally seen in later life from 60 to 100 in the general population. This is not to say that being older than 100 is a walk in the park, as matters presently stand. These individuals approach a 50% yearly mortality rate, are frail, and […]
Updated: 2025-01-17 05:34:53
A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual (left) shows a larger brain with more white matter compared with a brain image from a patient with sickle cell disease (right). Healthy individuals experiencing economic deprivation also had more-aged appearing brains.
Updated: 2025-01-16 04:07:49
Regular aerobic exercise could significantly reduce disease markers associated with Alzheimer's, new research has found. The findings provide new hope in the battle against this devastating disorder.
Updated: 2025-01-15 21:48:28
People who eat more red meat, especially processed red meat like bacon, sausage and bologna, are more likely to have a higher risk of cognitive decline and dementia when compared to those who eat very little red meat, according to a new study.
Updated: 2025-01-13 18:46:09
Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.
Updated: 2025-01-13 18:40:46
A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.
Updated: 2025-01-10 19:35:53
Cognitive profiles for early diagnosis of Dementia with Lewy bodies (DLB) have been outlined in a new study. Although DLB is the second most common neurodegenerative dementia following Alzheimer's Disease, it is usually misdiagnosed, preventing affected people from accessing care better tailored to their prognosis.
Updated: 2025-01-07 21:18:36
A study has found cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, not to be associated with an increased risk of such harm in individuals 90 and older.
Updated: 2025-01-06 03:07:28
A team has devised a more accurate way of measuring an indicator of kidney function known as glomerular filtration rate (GFR) by taking aging into account.
Updated: 2025-01-01 18:20:40
Scientists have identified the molecular changes that occur in the brains of aging mice and located a hot spot where much of that damage is centralized. The cells in the area are also connected with metabolism, suggesting a connection between diet and brain health.
