Updated: 2023-10-31 19:12:09
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help October 31st , 2023 Towards Clearance of Senescent Cells to Improve Heart Regeneration Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Senescent cells accumulate with age in tissues throughout the body . Cells enter a senescent state constantly throughout life
Updated: 2023-10-31 10:24:30
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help October 31st , 2023 Reviewing the Role of Insulin in Aging Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The relationship between insulin metabolism and aging is one of the most studied areas of the field , with decades of researchers putting in time to
Updated: 2023-10-31 10:11:45
The gut microbiome appears important to health, as judged by the changes in relative population sizes between species that take place across the course of aging, and the ability of reversing those changes to improve health and extend life in old animals. If the near future is restoration of a more youthful balance of microbial populations in the aged gut microbiome, to produce more beneficial metabolites and reduce inflammation, then the next step after that is to start engineering gut microbes to produce even greater effects. The example here produces poor, sex-specific effects in rats, but it is one example of a thousand different possibilities, many of which will turn out to be far more impressive. Engineered gut microbiota represents a new frontier in medicine, […]
Updated: 2023-10-30 19:22:20
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help October 30th , 2023 Glial Cell Mitochondrial Stress Can Indirectly Signal to the Whole Organism Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Glia of various sorts are supporting cells in the brain , assisting the function of neurons Dysfunction and stress
Updated: 2023-10-30 19:13:47
As little as 1 per cent reduction in deep sleep per year for people over 60 years of age translates into a 27 per cent increased risk of dementia, according to a study which suggests that enhancing or maintaining deep sleep, also known as slow wave sleep, in older years could stave off dementia.
Updated: 2023-10-30 10:22:17
A number of vertebrate species exhibit negligible senescence, meaning little to no functional degeneration over the course of their lives. Usually they also exhibit very long life spans for their size, and in comparison to near relative species that do exhibit evident aging. Researchers study these species in order to (a) identify important mechanisms of degenerative aging as targets for further research, as well as to (b) potentially find adjustments to cellular biochemistry that might stop a given mechanism from contributing to aging in our species. The first goal is much more feasible in the near term; it remains to be seen as to whether the second is even plausible to engineer in our lifetimes. A necessary first step in this field of research is […]
Updated: 2023-10-30 10:11:37
, Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help October 30th , 2023 Gingivitis Bacteria Causes Harms in the Heart , Impairing Already Poor Recovery from Heart Attack Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Inflammatory periodontal disease is caused by a specific bacterial species . The bacteria
Updated: 2023-10-27 19:01:57
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help October 27th , 2023 Senescent Cells Contribute to the Degeneration of the Retinal Vasculature Permalink With Comments Permalink No Comments Posted by Reason Read 1 Comment Add a Comment Senescent cells accumulate with age throughout the body . While their numbers remain a small fraction of all cells in a
Updated: 2023-10-27 10:22:25
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help October 27th , 2023 Sizable Mortality Risk Differences for Healthy versus Unhealthy Lifestyles in Later Life Permalink With Comments Permalink No Comments Posted by Reason Read 7 Comments Add a Comment Researchers here look at a sizable set of epidemiological data for people in their 70s , and note that
Updated: 2023-10-27 10:11:27
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help October 27th , 2023 Examining Human Brain Cell Changes in the Early Stages of Alzheimer's Disease Permalink With Comments Permalink No Comments Posted by Reason Read 1 Comment Add a Comment Prevention is both better than a cure and easier to achieve than a cure . Intervening early , prior to evident
Updated: 2023-10-20 15:57:08
Women with diets during middle age designed to lower blood pressure were about 17 percent less likely to report memory loss and other signs of cognitive decline decades later, a new study finds.
Updated: 2023-10-19 16:12:31
A team of researchers have mapped almost 6,000 proteins from different cell types within the eye by analyzing tiny drops of eye fluid that are routinely removed during surgery. The researchers used an AI model to create a 'proteomic clock' from this data that can predict a healthy person's age based on their protein profile. The clock revealed that diseases such as diabetic retinopathy and uveitis cause accelerated aging within specific cell types. Surprisingly, the researchers also detected proteins associated with Parkinson's disease within eye fluid, which they say could offer a pathway to earlier Parkinson's diagnoses.
Updated: 2023-10-18 21:19:14
A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause. It is known that a small molecule called nicotinamide adenine dinucleotide (NAD+) plays a critical role in this decline, and scientists have revealed how this happens and have identified potential new approaches to enhance reproductive longevity.
Updated: 2023-10-18 02:59:22
Research identifies links between gut bacteria, inflammation and brain changes associated with Alzheimer's disease. The findings suggest that Alzheimer's symptoms can be transferred via the gut microbiota.
Updated: 2023-10-17 05:35:17
Adults with attention-deficit/hyperactivity disorder (ADHD) are nearly three times more likely to develop dementia than adults without ADHD, according to a new study. The study followed more than 100,000 older adults in Israel over 17 years to examine if adults with ADHD are at increased risk for dementia, including Alzheimer's disease.
Updated: 2023-10-17 05:34:35
Researchers have shown female sex hormones play a significant role in how Alzheimer's manifests in the brain. The study also highlights the importance of developing therapeutic strategies focused on these hormonal connections. The research indicates a need to better understand the role of estradiol -- a form of the female sex hormone estrogen, used therapeutically to mitigate menopause symptoms -- in Alzheimer's disease.
Updated: 2023-10-13 20:07:33
Reducing overall calorie intake may rejuvenate your muscles and activate biological pathways important for good health, according to researchers. Decreasing calories without depriving the body of essential vitamins and minerals, known as calorie restriction, has long been known to delay the progression of age-related diseases in animal models. This new study suggests the same biological mechanisms may also apply to humans.
Updated: 2023-10-13 16:49:11
Researchers have developed a new test that can accurately measure biological aging in a clinical setting. The discovery was made while studying patients for the aging effects of chronic kidney disease.
Updated: 2023-10-12 01:24:27
A drug that boosts strength in injured or aging mice restores connections between nerves and muscle and suggests ways to combat weakness in humans due to aging, injury or disease.
Updated: 2023-10-11 23:22:59
Among people who report memory and thinking problems, some show no signs of a problem on standard tests, while others have subtle declines on their tests. A new study shows that people who have subtle problems with these tests may have an increased risk of developing mild cognitive impairment, which can be a precursor to dementia.
Updated: 2023-10-05 22:37:55
Alzheimer’s disease is the most common type of dementia, a disorder of progressively worsening memory and other thinking abilities. It rose up in the ranks of leading causes of death over the past several decades. It can also limit the duration of a working career, create uncertainty in the financial planning for retirement and rob patients of enjoyment and happiness in the final years. An effective treatment against this disease could give back to the patient the decision when to retire and improve quality of life in advanced age. Now, scientists are on the trail of a promising new therapeutic target – ABCA7, a protein known to protect from Alzheimer’s disease. The study uncovers new information about the relationship between ABCA7, cholesterol, and inflammation in human brain cells.
Updated: 2023-10-05 16:08:02
As we age, many of us will eventually need hearing aids. In some cases, the reason for this may be a signaling pathway that controls auditory sensory cell function and is downregulated with age.
Updated: 2023-10-04 18:24:03
In a study on the prevalence of attention-deficit/hyperactivity disorder (ADHD) and its association with crash risk among older adult drivers, researchers found that older adult drivers with ADHD are at a significantly elevated crash risk compared with their counterparts without ADHD. Outcomes included hard- braking events, and self-reported traffic ticket events, and vehicular crashes. Until now research on ADHD and driving safety was largely limited to children and young adults, and few studies assessed the association of ADHD with crash risk among older adults.
Updated: 2023-10-04 15:52:24
A research team has achieved a significant breakthrough in the treatment of age-related diseases. This groundbreaking development is set to redefine the future of healthcare and usher in a new era of targeted therapeutic interventions.
