Updated: 2023-06-30 10:22:21
Why do moles tend to grow hair, even in older people who are well advanced in loss of hair growth elsewhere on the skin? Researchers here provide evidence for this to be due to signals secreted by senescent melanocyte cells. This may provide a path to encourage a reversal of hair loss in all of the various poorly-understood circumstances that lead to balding. Inducing an additional burden of cellular senescence in skin is not desirable, but a better understanding of exactly how the senescence-associated secretory phenotype (SASP) encourages hair growth could provide a more direct way to provide only the necessary signals to the skin. Niche signals maintain stem cells in a prolonged quiescence or transiently activate them for proper regeneration. Altering niche signalling can […]
Updated: 2023-06-30 10:11:10
, , Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 30th , 2023 Rat Kidneys Vitrified , Warmed with Magnetic Nanoparticles , then Transplanted Successfully Permalink Read 1 Comment Add a Comment Posted by Reason Another step forward for the magnetic nanoparticle approach to thawing vitrified tissues was recently reported . Vitrification for
Updated: 2023-06-29 19:12:46
It is becoming clear that a major factor in the highly variable quality of first generation stem cell therapies has a lot to do with the degree to which cells become senescent when expanded in culture prior to injection. This can vary widely with small differences in culturing technique, even given a similar protocol, or the same team performing the same processes from one batch to the next, absent very rigorous quality control mechanisms of the sort typically not used by clinics in the medical tourism industry. The research community is looking into the use of senolytics to improve outcomes, but it is unclear as to whether this or any of the other possible approaches to minimize cellular senescence in stem cell cultures have yet […]
Updated: 2023-06-29 10:22:51
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 29th , 2023 Senescent Astrocytes in the Aging of the Brain Permalink No Comments Yet Add a Comment Posted by Reason Cellular senescence in the supporting cells of the brain is increasingly implicated in the onset and progression of neurodegenerative conditions Senescent cells accumulate with age ,
Updated: 2023-06-29 10:11:06
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 29th , 2023 The Interaction of Calorie Restriction and Circadian Rhythm Permalink No Comments Yet Add a Comment Posted by Reason Researchers here note that feeding and fasting time appears to meaningfully change the effects of long-term calorie restriction on life span in short-lived mammals . Much
Updated: 2023-06-28 19:04:33
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 28th , 2023 Reviewing the Role of TFEB Upregulation in Approaches Shown to Slow Aging Permalink Read 1 Comment Add a Comment Posted by Reason Most of the varied approaches shown to modestly slow the progression of aging appear to operate through a small number of common mechanisms , largely
Updated: 2023-06-28 10:22:04
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 28th , 2023 Frailty Correlates with Cognitive Decline Permalink Read 1 Comment Add a Comment Posted by Reason Frailty is known to correlate with risk of dementia and here researchers observe an inverse correlation with cognitive function in a large study population of older adults . The many
Updated: 2023-06-28 10:11:14
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 28th , 2023 Towards Repair of the Leaking Blood-Brain Barrier Permalink Read 1 Comment Add a Comment Posted by Reason Researchers here report on an effort to find small molecule drugs that can favorably adjust cell metabolism in the blood-brain barrier in order to prevent some fraction of the
Updated: 2023-06-27 19:02:04
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 27th , 2023 The Contribution of Transposons to Differences in Life Span Between Species Permalink No Comments Yet Add a Comment Posted by Reason Transposable elements in the nuclear genome also called transposons , are remnant DNA sequences left over from past , often ancient viral infections . A
Updated: 2023-06-27 10:19:48
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help June 27th , 2023 Senolytic Treatment Improves Neurogenesis in Aged Killifish Permalink Read 1 Comment Add a Comment Posted by Reason Killifish exhibit proficient regeneration , but lose regenerative capacity with advancing age . Some of this loss is due to the growing presence of lingering senescent
Updated: 2023-06-26 21:42:46
In a study that followed more than 2,000 community-dwelling older adults over eight years, researchers say they have significant new evidence of a link between decreased sense of smell and risk of developing late-life depression.
Updated: 2023-06-21 15:54:27
In an eight-year study of more than 600 community-dwelling older adults, researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty. The study is novel and expands on previous work, the investigators say, because it focused on mitochondrial DNA rather than solely genomic DNA, as previously reported.
Updated: 2023-06-15 23:31:30
A team or researchers reports the first Aging Fly Cell Atlas (AFCA), a detailed characterization of the aging process in 163 distinct cell types in the laboratory fruit fly. Their in-depth analysis revealed that different cell types in the body age differently, each cell type following a process involving cell type-specific patterns. AFCA provides a valuable resource for researchers in the fruit fly and aging communities as a reference to study aging and age-related diseases and to evaluate the success of anti-aging strategies.
Updated: 2023-06-09 00:56:54
A study finds that deficiency of taurine, a molecule produced in our bodies, drives aging, and taurine supplements can improve health and increase lifespan in animals.
Updated: 2023-06-08 05:10:31
A team of scientists has discovered that IL-17 protein plays a central role in skin aging. The study highlights an IL-17-mediated ageing process to an inflammatory state.
Updated: 2023-06-07 05:40:48
Researchers found where plaques are found in the brain may impact hearing in Alzheimer's disease.
Updated: 2023-06-07 05:38:55
They're a marine delicacy loved across Asia, but the humble sea cucumber is also proving to be a key ingredient in preventing diabetes, according to new research.
Updated: 2023-06-06 16:15:03
Researchers have shown that defective myelin actively promotes disease-related changes in Alzheimer's disease.
