Updated: 2023-08-31 19:34:18
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 31st , 2023 Physical Fitness Correlates with Slower Epigenetic Aging in Newer DNA Methylation Clocks Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Epigenetic clocks that measure chronological or biological age are at present largely based on patterns
Updated: 2023-08-31 10:22:35
Naked mole rats live far longer than similarly sized mammals, and are near immune to cancer. One of the mechanisms of cancer resistance involves the production of a different form of high molecular weight hyaluronan, and much more of it, improving the anti-cancer mechanism of contact inhibition. In addition, other mechanisms derived from changes in hyaluronan may affect life span through improved cellular function, but this is less well explored. Researchers here take the naked mole-rat version of the gene for high molecular weight hyoluronan, hyaluronan synthase 2, and put it into mice. The result is less cancer, improved metabolism, and longer lives. Naked mole rats are mouse-sized rodents that have exceptional longevity for rodents of their size; they can live up to 41 years, […]
Updated: 2023-08-31 10:11:18
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 31st , 2023 Sex Differences in Microglial Senescence in the Context of Alzheimer's Disease Permalink With Comments Permalink No Comments Posted by Reason Read 1 Comment Add a Comment Why are two-thirds of Alzheimer's patients women Women live longer than men , making up an ever larger share of the
Updated: 2023-08-30 19:16:21
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 30th , 2023 Intermittent Fasting Reduces Pathology in a Mouse Model of Alzheimer's Disease Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The sizable body of work produced on calorie restriction and fasting over the last twenty years is supportive of
Updated: 2023-08-30 18:36:03
Your source for the latest research news : Follow Facebook Twitter LinkedIn : Subscribe RSS Feeds advertisement Science News from research organizations Educational attainment protects against a genetic risk factor for Alzheimer's disease : Date August 30, 2023 : Source Mass General Brigham : Summary A new study further illustrates that when it comes to risk of Alzheimer's disease , even genetically determined forms of the disease , genetics is only one piece of the puzzle . Researchers investigated the influence of genetics and educational attainment on cognitive decline by studying data from 675 people who carry a mutation that predisposes them to early onset Alzheimer's disease . Carriers of this mutation known as PSEN1 E280A have a median age of 49 for onset of dementia . The team
Updated: 2023-08-30 18:19:56
Scientists have made a 'paradigm shifting' discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer's disease and potentially Down syndrome.
Updated: 2023-08-30 10:22:01
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 30th , 2023 PGC-1α4 Gene Therapy Reduces Sarcopenia and Metabolic Disease in Aged Mice Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Researchers here demonstrate that aged muscle metabolism can be improved via gene therapy to deliver a short isoform
Updated: 2023-08-30 10:14:18
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 30th , 2023 A Large Study of Immune Aging in T Cell and Natural Killer Cell Populations Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The overall population size of broad immune cell categories , such as T cells remains remarkably consistent across a
Updated: 2023-08-29 19:22:33
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 29th , 2023 A Perspective on the Coming Regulatory Shift to Approval of Drugs to Treat Aging Permalink With Comments Permalink No Comments Posted by Reason Read 1 Comment Add a Comment At some point , regulatory bodies that oversee the development of new medicine will accept that therapies can
Updated: 2023-08-29 19:16:49
Researchers have shown that the content of diet in yeast, rather than caloric intake, influences yeast health in later stages of their lifecycle. The different diet placed cells on a path to age healthily and avoid aging pathologies, though they did not live longer.
Updated: 2023-08-29 18:00:01
Researchers investigated the associations of weight changes later in life with exceptional longevity and found that women who maintained their body weight after age 60 were more likely to reach exceptional longevity.
Updated: 2023-08-29 10:22:51
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 29th , 2023 Quality of Diet versus Pace of Aging Permalink With Comments Permalink No Comments Posted by Reason Read 1 Comment Add a Comment Given the advent of various clocks that measure biological age , one might expect that the research community will repeat and update past efforts to quantify
Updated: 2023-08-29 10:11:34
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help August 29th , 2023 Physical Fitness Correlates with a Lower Risk of Atrial Fibrillation and Stroke Permalink With Comments Permalink No Comments Posted by Reason Read 1 Comment Add a Comment As one might expect , people who better maintain physical fitness into later life exhibit lesser degrees of
Updated: 2023-08-23 21:54:02
In a groundbreaking endeavor, researchers have successfully transferred a longevity gene from naked mole rats to mice, resulting in improved health and an extension of the mouse's lifespan. The research opens exciting possibilities for unlocking the secrets of aging and extending human lifespan.
Updated: 2023-08-10 16:03:38
New research has successfully reversed hearing loss in mice. Scientists used a genetic approach to fix deafness in mice, restoring their hearing abilities in low and middle frequency ranges.
Updated: 2023-08-09 21:47:27
People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research. This study does not prove that acid reflux drugs cause dementia; it only shows an association.
Updated: 2023-08-09 21:47:24
Promising preclinical results show hematopoietic stem cell therapy was effective in rescuing memory loss, neuroinflammation and beta amyloid build-up in a mouse model of Alzheimer's disease.
Updated: 2023-08-04 05:36:59
The projected cost of caring for millions of individuals who have Alzheimer's disease (AD) worldwide will exceed a $1 trillion in a few years. In addition to the enormous health burden, patients and their caregivers experience financial, physical and psychological strain. A theory regarding repeated drug failure in AD is that patients undergoing experimental therapies are selected too late in the disease process. Therefore, it is important to identify patients at a high risk of progression to AD in early stages of the disease. To help identify persons who could benefit from early interventions, researchers from Boston University have developed a deep learning framework that can stratify individuals with mild cognitive impairment (MCI) based on their risk of advancing to AD.
Updated: 2023-08-04 02:38:52
A research team has identified a novel target responsible for aging-related chronic metabolic disorders.
