Updated: 2024-04-30 10:22:29
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 30th , 2024 Cellular Senescence in Neurodegenerative Conditions Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment This open access review paper covers the high points of what is presently known of the contribution of senescent cells to neurodegenerative
Updated: 2024-04-30 10:11:12
There is a bidirectional relationship between declining kidney function and raised blood pressure, two prominent features of aging. The kidney is responsible for managing blood volume (one contribution to blood pressure) by adjusting the amount of water in blood as the bloodstream is filtered, a process that depends on some combination of the sensing of soluble factors and pressure. These complex systems fail with age in ways that can lead to raised blood pressure. Raised blood pressure in turn can damage the kidney directly, but also indirectly disrupt the balance of blood pressure control systems elsewhere in the body, such as via the constriction and dilation of blood vessels, or heart rate, that interact with those of the kidney via signaling molecules. It is a […]
Updated: 2024-04-29 18:01:25
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 29th , 2024 Presence of Cardiometabolic Disease Correlates with Accelerated Brain Aging Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment It is well known that metabolic dysfunction and cardiovascular disease correlate well with an accelerated onset and
Updated: 2024-04-29 15:58:57
A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers.
Updated: 2024-04-29 10:22:46
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 29th , 2024 A Progressive Failure of Glucose Regulation in the Aging Brain Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment There has long been a school of thought on Alzheimer's disease that consideres it a form of diabetes in which dysregulated glucose
Updated: 2024-04-29 10:11:33
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 29th , 2024 Many Epigenetic Clocks Differ by Time of Day Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Because epigenetic clocks are produced from DNA methylation data via machine learning approaches , correlating patterns of change with chronological
Updated: 2024-04-26 20:49:53
Patients with growth hormone receptor deficiency, or Laron syndrome, appear to have lower than average risk factors for cardiovascular disease, according to a new study.
Updated: 2024-04-26 10:22:11
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 26th , 2024 Calorie Restriction and Fasting Benefit the Aging Heart Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The practice of calorie restriction intermittent fasting and related strategies such the fasting mimicking diet are thought to produce
Updated: 2024-04-26 10:11:07
Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 26th , 2024 MYC and USF1 are Downregulated in Aged Human Macrophages Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Researchers here explore age-related changes that take place in the innate immune cells known as macrophages as well as the precursor
Updated: 2024-04-25 19:22:21
This messy popular science article is an essay length expression of futility on the part of a journalist who accepts that he is not equipped to understand the field of aging research and the longevity industry that has arisen in the past decade. One can talk to the talking heads, but they will all say something different. One can look for proof of efficacy for specific approaches, and find only contradictory data, or only compelling animal data, or only small effect sizes, and a lack of the sort of certainty that arises from large human trials. Those trials are still in the future for near every approach to the treatment of aging that might work. Like most tours of the field written by journalists, the […]
Updated: 2024-04-24 15:16:56
Cognitive decline among Black women linked to poor heart health in middle age.
Updated: 2024-04-23 19:59:05
Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study. The phenomenon may provide an opportunity to learn more about the neurodegeneration process, and the technique used to make this discovery is readily applicable to other inquiries about unique populations of cells in the brain.
Updated: 2024-04-22 04:07:09
A specific protein, TP53INP2, might prevent muscle loss associated with aging. A new study indicates that high levels of this protein are linked to greater muscle strength and healthier aging. This discovery paves the way for new treatments that could enhance the quality of life for the elderly.
Updated: 2024-04-22 04:06:21
Middle-aged and older adults believe that old age begins later in life than their peers did decades ago, according to a new study.
Updated: 2024-04-17 22:28:16
The rate at which human cells age is influenced by multiple interconnected factors. New research examined how restricting calories influences telomere length and biological aging.
Updated: 2024-04-17 22:27:03
In a new study, researchers show that elevated levels of proteins related to cellular senescence, or aging, in the blood and the placenta are linked to this form of heart failure.
Updated: 2024-04-15 15:05:38
The first comprehensive cell atlas of aging human muscle reveals the intricate genetic and cellular processes behind muscle deterioration and mechanisms to counteract it.
Updated: 2024-04-10 15:27:17
Researchers have discovered the connection between aldehydes, organic compounds produced by cells as part of metabolic processes, and rapid aging. Their findings indicate a potential treatment for diseases that lead to accelerated aging as well as a means to counteract aging in healthy people by controlling exposure to aldehyde-inducing substances including alcohol, pollution, and smoke.
Updated: 2024-04-10 15:27:06
Scientists have identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV.
Updated: 2024-04-08 19:04:49
Pregnancy may carry a cost, reports a new study. The research shows that women who reported having been pregnant looked biologically older than women who had never been pregnant, and women who had been pregnant more often looked biologically older than those who reported fewer pregnancies.
Updated: 2024-04-05 17:04:46
Certain RNA molecules in the nerve cells in the brain last a life time without being renewed. Neuroscientists have now demonstrated that this. RNAs are generally short-lived molecules that are constantly reconstructed to adjust to environmental conditions. The research group hopes to decipher the complex aging process of the brain and gain a better understanding of related degenerative diseases.
