• NPTX2 Involved in Neurodegeneration Driven by TDP-43 Aggregation

    Updated: 2024-02-29 19:31:21
    Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help February 29th , 2024 NPTX2 Involved in Neurodegeneration Driven by TDP-43 Aggregation Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Altered , misfolded forms of TDP-43 are thought to contribute to neurodegeneration in a number of age-related conditions ,

  • Particulate Air Pollution Correlates with Risk of Alzheimer's Disease

    Updated: 2024-02-29 11:22:26
    Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help February 29th , 2024 Particulate Air Pollution Correlates with Risk of Alzheimer's Disease Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Researchers here use data on air pollution from a single US metropolitan area to show a correlation with Alzheimer's

  • Aged Pancreatic Fibroblasts Secrete GDF-15, Encouraging Tumor Growth

    Updated: 2024-02-28 11:22:32
    Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help February 28th , 2024 Aged Pancreatic Fibroblasts Secrete GDF-15, Encouraging Tumor Growth Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Researchers here note one of a broad range of examples in which age-related changes in the state and behavior of

  • MDM2 Inhibition Reduces Loss of Synapses in a Cell Culture Model

    Updated: 2024-02-28 11:11:12
    Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help February 28th , 2024 MDM2 Inhibition Reduces Loss of Synapses in a Cell Culture Model Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment Loss of synaptic connections between neurons is one of the harmful outcomes of neurodegenerative conditions such as

  • The Gut Microbiome and Alzheimer's Disease

    Updated: 2024-02-27 11:22:09
    Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help February 27th , 2024 The Gut Microbiome and Alzheimer's Disease Permalink With Comments Permalink No Comments Posted by Reason No Comments Yet Add a Comment The balance of microbial populations making up the gut microbiome changes with age , both a loss of microbes generating beneficial metabolites and

  • Repeated Cycles of a Fasting-Mimicking Diet Reduce Measures of Biological Age

    Updated: 2024-02-27 11:11:17
    Development of the fasting-mimicking diet resulted from efforts to find out where the beneficial response to fasting begins; how much can one eat and still be effectively fasting? Where is the trigger point? An individual can in fact gain a majority of the benefits of fasting at around 600 calories per day, and five days of fasting mimicking produces beneficial changes in metabolism that can last for months. A formal fasting mimicking diet was created has undergone clinical trials as an adjuvant therapy in the treatment of cancer. In practice fasting mimicking is easily carried out at home without the formal diet: count calories, eat sensibly. Here, researchers show that Klemera-Doubal biological age is lowered by a few years following fasting mimicking, alongside a measure […]

  • Telomere Length as a Target for Therapy

    Updated: 2024-02-26 19:22:55
    Average telomere length in a tissue is some reflection of (a) stem cell activity and (b) pace of cell division. Telomeres, repeated DNA sequences at the ends of chromosomes, lose some of their length with each cell division, and cells self-destruct or become senescent when telomeres become too short. This limits the ability of somatic cells to replicate, reducing the odds that a given cell will mutate to become cancerous by imposing a limit on cell activity and cell life span, enforcing turnover of cells in tissues. Stem cells, in comparison, are a small, well protected, privileged set of cell populations that use telomerase to extend their telomeres after cell division. Stem cells produce daughter somatic cells with long telomeres to replace those lost to […]

  • Yoga provides unique cognitive benefits to older women at risk of Alzheimer's disease

    Updated: 2024-02-26 16:46:45
    A new study found Kundalini yoga provided several benefits to cognition and memory for older women at risk of developing Alzheimer's disease including restoring neural pathways, preventing brain matter decline and reversing aging and inflammation-associated biomarkers -- improvements not seen in a group who received standard memory training exercises.

  • Scientists discover link between leaky gut and accelerated biological aging

    Updated: 2024-02-22 02:39:10
    A professor has demonstrated a connection between viral damage to the gut and premature biological aging.

  • How AI can help spot early risk factors for Alzheimer's disease

    Updated: 2024-02-21 21:03:14
    Scientists have found a way to predict Alzheimer's Disease up to seven years before symptoms appear by analyzing patient records with machine learning.

  • Fasting-like diet lowers risk factors for disease, reduces biological age in humans

    Updated: 2024-02-20 19:45:36
    Cycles of a diet that mimics fasting can reduce signs of immune system aging, as well as insulin resistance and liver fat in humans, resulting in a lower biological age, according to a new study.

  • New genetic therapy holds promise for ALS and frontotemporal dementia

    Updated: 2024-02-16 18:58:46
    Neuroscientists have developed a single-dose genetic medicine that has been proven to halt the progression of both ALS and FTD in mice -- and may even offer the potential to reverse some of the effects of the fatal diseases. It may also hold opportunities for treating more common forms of dementia, such as Alzheimer's disease.

  • New epigenetic clocks reinvent how we measure age

    Updated: 2024-02-15 01:33:41
    Investigators unveil a new form of epigenetic clock -- a machine learning model designed to predict biological age from DNA structure.

  • Non-invasive techniques to detect skin cancer

    Updated: 2024-02-12 18:32:16
    A study has demonstrated that the appearance of ageing skin looks noticeably different compared to younger skin, when examined under polarized laser light. The scientists believe that their new finding could pave the way for new, non-invasive light-based techniques to detect diseases, including cancer, in older individuals. This could significantly enhance early-stage treatment options for various skin conditions.

  • Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

    Updated: 2024-02-08 00:46:21
    The drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to new research. The study does not prove that erectile dysfunction drugs reduce the risk of Alzheimer's disease. It only shows an association.

  • Study finds strongest evidence to date of brain's ability to compensate for age-related cognitive decline

    Updated: 2024-02-06 19:49:44
    Scientists have found the strongest evidence yet that our brains can compensate for age-related deterioration by recruiting other areas to help with brain function and maintain cognitive performance.

  • How ovarian tissue freezing could prevent menopause -- possibly forever

    Updated: 2024-02-06 19:49:04
    A new paradigm around the biological processes of menopause is capturing the attention of scientists. The primary question: can menopause be delayed in healthy women, allowing them to extend their child-bearing years -- and perhaps even forestall some of the health risks and uncomfortable symptoms linked to plummeting estrogen levels?

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