Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 1st , 2021 Naked Mole Rats Employ Cholesterol Metabolism to Enable Cells to Resist the Senescent State Permalink No Comments Yet Add a Comment Posted by Reason Naked mole-rats exhibit an unusually longevity , with a life span something like nine times as long as that of equivalently sized mammals .

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help April 1st , 2021 Age-Related Upregulation of Autophagy as a Possible Contribution to Bat Longevity Permalink No Comments Yet Add a Comment Posted by Reason Bat species include many that are long-lived for their size Flying species in general are long lived one can find many similarities in metabolism

, Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help March 31st , 2021 Supplementation with Glutathione Precursors Improves Mitochondrial Function , Reduces Oxidative Stress and Inflammation Permalink No Comments Yet Add a Comment Posted by Reason Mitochondria are the power plants of the cell , turning out the chemical energy store molecule ATP that is

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help March 31st , 2021 PPARα Slows Atherosclerosis by Inhibiting Vascular Cellular Senescence Permalink No Comments Yet Add a Comment Posted by Reason It may turn out to be the case that many mechanisms of cellular regulation that slow aspects of aging function , at least in part , by slowing the pace at

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help March 31st , 2021 Engineered Cells Drive Blood Vessel Formation Following Stroke to Restore Lost Function in Mice Permalink No Comments Yet Add a Comment Posted by Reason Researchers have recently demonstrated a cell therapy approach that drives greater blood vessel formation in the brain . In mice this

James Peyer was involved in the aging-focused fund Apollo Ventures before he moved on to the more recent venture industry initiative that evolved into Cambrian Biopharma. Cambrian is arguably even more focused on creating new biotech startups to treat aging, rather than investing in existing companies, than is the case for Apollo. Many venture capitalists are coming to the conclusion that the pace at which new biotech companies in this space are arising is too slow to provide sufficient opportunities for the capital that could be harnessed to produced progress. That pace must thus be accelerated. Peyer is a regular on the conference circuit, and can be relied upon to give interesting, thoughtful presentations on the state of the science, the state of the funding, […]

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help March 30th , 2021 Gene Therapy to Reduce Tau Expression in Mouse Models of Tauopathy Permalink No Comments Yet Add a Comment Posted by Reason Tau is one of the few proteins in the body capable of becoming altered in ways that form harmful aggregates , capable of disrupting cell function or killing cells

Some fraction of aging in the brain is due to a reduced blood flow to brain tissue, and thus a reduced delivery of nutrients and oxygen to brain cells. Vascular aging reduces the density of capillary networks in tissue, and increases stiffness of blood vessels. Equally, a sedentary lifestyle - and, later, heart failure - reduces the ability of the heart to pump blood uphill to the brain. Structured exercise programs consistent demonstrate health benefits in older individuals, likely because near everyone in later life fails to undertake sufficient exercise. Here, researchers show that one of those benefits is an increased flow of blood to the brain, an outcome that should slow the progression of neurodegeneration to some degree. As many as one-fifth of people […]

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help March 29th , 2021 Finding the Limits of Amyloid Clearance as a Treatment for Alzheimer's Disease Permalink No Comments Yet Add a Comment Posted by Reason Alzheimer's disease is associated with a slow buildup of amyloid-β aggregates in the brain over the years of later life . The amyloid cascade

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