Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 19th , 2021 The Age-Related Decline of Energy Metabolism in Myeloid Cells as an Important Cause of Neurodegeneration Permalink No Comments Yet Add a Comment Posted by Reason Today's open access editorial discusses one quite specific consequence of the age-related disruption of energy metabolism

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 19th , 2021 The Longevity Biotech Association Launches Permalink Read 1 Comment Add a Comment Posted by Reason At first glance , with only a few exceptions in the initial membership , the newly launched Longevity Biotech Association is an advocacy group for the small molecule , stress response

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 19th , 2021 Studying the Comparative Biology of Aging in Rockfish Species Permalink No Comments Yet Add a Comment Posted by Reason Rockfish species vary widely in lifespan . Some even exhibit negligible senescence showing few signs of aging across the majority of their long life spans . When

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 18th , 2021 Some Cell Therapies Reduce Inflammation Precisely Because the Transplanted Cells Die Permalink Read 1 Comment Add a Comment Posted by Reason First generation stem cell therapies have been demonstrated to reduce chronic inflammation but are unreliable when it comes to producing other

For reasons yet to be determined, the composition of the skin microbiome changes with age. It is also unclear as to whether these changes contribute to skin aging in any meaningful way, or are instead a consequence of skin aging. Researchers here perform a proof of concept study to identify bacterial activities that differ in the microbiome of old versus young skin. There is little to be learned from these initial results, but in principle a much more comprehensive set of data might point the way towards specific experiments that could be conducted, changing the balance of populations in the skin microbiome in measured ways to see if the function of aged skin improves as a result. The human skin is inhabited by a large […]

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 18th , 2021 A Senolytic Treatment Improves Visual Function in a Small Trial for Macular Degeneration Permalink Read 2 Comments Add a Comment Posted by Reason UNITY Biotechnology recently reported positive results for their senolytic drug candidate UBX1325 probably derived from navitoclax

, Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 17th , 2021 Results From a Small , Informal Trial of Telomerase and Klotho Gene Therapy for Alzheimer's Disease Permalink Read 2 Comments Add a Comment Posted by Reason Bioviva was at one point developing telomerase gene therapies work that has transitioned into the medical tourism industry

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 17th , 2021 IKK NF-κB Activation as a Target for Senotherapeutics Permalink Read 1 Comment Add a Comment Posted by Reason The accumulation of senescent cells in later life is a contributing cause of aging . While these errant cells never amount to more than a tiny fraction of all cells in a

Asking whether an age-associated disease is a part of normal aging is an exercise in boundary drawing. The very definition of an age-related disease as something distinct from aging is the result of past boundary drawing. Many of these boundaries are quite arbitrary. Aging is a complex phenomenon, and people like to lay taxonomies on top of a complex space of many interacting mechanisms in order to try to make some sense of it. The results are sometimes helpful, sometimes not. The discussion in this open access paper is perhaps a good example of where the exercise of drawing boundaries can lead, while trying to separate out categories from the interplay of cancer, precancerous processes, and mechanisms of aging. Myelodysplastic syndromes (MDS) are hematopoietic stem […]

Home FAQ Fund Research Services Investing Therapies Newsletter Archives Press Room Resources About Fight Aging Do you want to live a longer life in good health Simple practices can make some difference , such as exercise or calorie restriction . But over the long haul all that really matters is progress in medicine : building new classes of therapy to repair and reverse the known root causes of aging . The sooner these treatments arrive , the more lives will be saved . Find out how to help November 16th , 2021 Evidence for Earlier Life Use of Some Senolytics to be Detrimental in Female Mice Permalink Read 11 Comments Add a Comment Posted by Reason Senescent cell accumulation is an important contributing cause of aging . Senescent cells secrete a mix of signals that provokes growth and

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