Re: Can dry loading be used on reverse phase silica?
Updated: 2024-02-29 07:33:22
I preferre wet-loading, if your sample does not dissolve in the eluent you should change it, for example use toluene instead of hexane. I think generally you get a more narrow band of the sample if you use wet-load and thus better separation. I have never tried dry-loading a RP column.